February 7
For those interested in understanding some of the basic biology underlying the development of CRISPR, the online resources cited previously may be helpful. In addition, I have created a series of PowerPoint presentations that I hope will help guide you through the thicket of information (I’m thinking now of Brer Rabbit saying “Oh, please Brer Fox, whatever you do, please don’t throw me in that briar patch!”).
The PowerPoint files below are generously illustrated, but most of the explanatory information is given in the Notes section of each slide. To view the Notes, select Notes Page, as shown below:
Chromosomes, Genes and the “Central Dogma”
Proteins, the Genetic Code and Mutations
DNA Sequencing, SNPs and Mutations
CRISPR as a bacterial defense system
Brave New World (coming!)
The controversial Heroes of CRISPR paper by Eric Lander
A one-page opinion piece, published in Nature, in which George Church argues that we should encourage, not restrict, research on germline gene editing.
Picture credits